Thanks to all for the great advice - a lot of great reading on the forum.
Still planning first visit to BKK and from all I have read it seems that the hotel location is central to ease of mobility.
Whether it is bringing a girl back to room (no interest in on site ST rooms), shopping, BTS, freelancers in vicinity and of course Nana Plaza for me, location is important.
Given that I'd like a medium priced hotel, what choices would you recommend to a first time visitor?
Many thanks!