I leave from my house in Florida usually between 4 and 5 AM, to go to the airport, after typically not being able to sleep the night before. The flight then goes to Detroit, or Atlanta, with a layover, then the long trip over Canada, and Alaska, then down to Japan, with a short layover; and then on to Bangkok, or Manila, with arrival at around 11PM the day after I left. After luggage and immigration is out of the way, its time to deal with the taxi and the hotel before I get a chance to relax, and by then it is in the early hours of day number 3 of my trip, by the local time. There is no possible way to not be affected by a jolt to your system like that. Back in the States, daylight savings time throws everyone out of wack for days and sometimes weeks, and that is a one hour change without travel. I drink lots of water, and I sleep when able, but the best thing you can do is to just try and ignore it and not dwell on it too much.